{"id":36,"date":"2024-10-02T13:28:16","date_gmt":"2024-10-02T17:28:16","guid":{"rendered":"https:\/\/cecas.clemson.edu\/nbm2\/?page_id=36"},"modified":"2026-03-19T10:31:14","modified_gmt":"2026-03-19T14:31:14","slug":"publications","status":"publish","type":"page","link":"https:\/\/cecas.clemson.edu\/nbm2\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"\n

New Publications after joining Clemson <\/strong><\/p>\n\n\n\n

    \n
  1. Lou, L., Paolino, L., Rubfiaro, A. S., He, J., & Agarwal, A. (2026). Gold Nanorods in Cardiac Millitissues: Assessing Mechanical and Contractile Dynamics in a Living Engineering Myocardium Model.\u00a0Advanced Materials Technologies<\/em>, e01716. https:\/\/doi.org\/10.1002\/admt.202501716<\/a><\/li>\n\n\n\n
  2. Zhou, H., Wang, J., & Lou, L. (2026). Nonwoven Membranes for Seawater Desalination: Structural Design, Functionalization Strategies, and System-Level Performance.\u00a0Textile Science & Research Journal<\/em>,\u00a02<\/em>(1), 27-52. https:\/\/doi.org\/10.63456\/tsrj-2-1-37<\/a><\/li>\n\n\n\n
  3. Agarwal, Arvind, MarkondeyaRaj PULUGURTHA, Lihua Lou, and Ghaleb Saleh Ghaleb Al-Duhni. “Polymer nanocomposite flexible films for electromagnetic interference shielding.” U.S. Patent 12,416,104, issued September 16, 2025. US12546032B1 – Polymer nanocomposite flexible films for electromagnetic interference shielding – Google Patents<\/a><\/li>\n\n\n\n
  4. Vijayan, V., & Lou, L. (2026). Design Principles and Mechanics: A Review of Emerging Paradigms in Intervertebral Disc Regeneration and Replacement.\u00a0Macromolecular Materials and Engineering<\/em>,\u00a0311<\/em>(2), e70199. https:\/\/doi.org\/10.1002\/mame.70199<\/a><\/li>\n\n\n\n
  5. Murickan, Rony Thomas, Lihua Lou, Denny John, Anil Lama, Abhijith Kunneparambil Sukumaran, Luiza Benedetti, Suleiman Muktari, and Arvind Agarwal. “Shape Memory Behavior of Electrospun Graphene Nanoplatelets\u2010Reinforced Polyurethane Nanofibers Under a Constrained Recovery Approach.”\u00a0Polymer Engineering & Science<\/em>\u00a0(2026). https:\/\/doi.org\/10.1002\/pen.70433<\/a><\/li>\n\n\n\n
  6. Kolte, Sumit Suryakant, Siddhi Sunil, Atharva Harinath Shastri, Vinayak Vijayan, and Lihua Lou. 2026. “Biopolymer-Based Adhesives for Biomedical and Industrial Use: Recent Advances, Challenges and Future Directions” Adhesives<\/em> 2, no. 1: 3. https:\/\/doi.org\/10.3390\/adhesives2010003 <\/li>\n\n\n\n
  7. Chauhan, Aditya, Ashfaqul Khadem, and Lihua Lou. “Cerium Oxide Enhanced Electrospun PVDF Nanofibers: Nanoscale Surface Mapping Towards Biomedical Scaffold Development.” (2025).<\/li>\n\n\n\n
  8. Kolte, Sumit, Vinayak Vijayan, and Lihua Lou. “Assessment of Auxetic and Nanocomposite Designs for Mimicking Natural Intervertebral Disc Behavior.” (2025).<\/li>\n\n\n\n
  9. Shastri, A., Sunil, S., Vijayan, V., & Lou, L. (2025). Design and Fabrication of a 4D-Printed Human Hand with Electrically Driven Muscle-Like Actuation.<\/li>\n\n\n\n
  10. Sunil, S., Khadem, A., Vijayan, V., & Lou, L. (2025). Mechanical Modeling of Biomimetic Scaffolds to Recreate Enthesis Function.<\/li>\n\n\n\n
  11. Agarwal, A., PULUGURTHA, M., Lou, L. and Al-Duhni, G.S.G., Florida International University FIU, 2025. Polymer nanocomposite flexible films for electromagnetic interference shielding<\/em>. U.S. Patent 12,416,104. US12416104B1 – Polymer nanocomposite flexible films for electromagnetic interference shielding – Google Patents<\/a><\/li>\n\n\n\n
  12. Yang, J., Wang, H., Lou, L. and Meng, Z. A Review of Chitosan-Based Electrospun Nanofibers for Food Packaging: From Fabrication to Function and Modeling Insights. Nanomaterials<\/em>, 15<\/em>(16), p.1274. August 2025 https:\/\/doi.org\/10.3390\/nano15161274<\/a> <\/li>\n\n\n\n
  13. Cruz, O.B., Lou, L., Mohammed, S.M.A.K., Murickan, R.T., Benedetti, L., Lin, Y.M., Dolmetsch, T. and Agarwal, A. Wearable, Ultralow Power, and Needleless Electrospinning Equipment for Cannabidiol-Loaded Patch Fabrication. ACS Applied Materials & Interfaces<\/em>. August 2025 https:\/\/doi.org\/10.1021\/acsami.5c14853<\/a><\/li>\n\n\n\n
  14. Lou, L., Nair, A.B., and Agarwal, A. Nanoindentation-Driven Insights into the Micro-Mechanical and Viscoelastic Behaviors of Porcine Atria and Ventricles. ACS Biomaterials Science & Engineering<\/a> July 2025 https:\/\/doi.org\/10.1021\/acsbiomaterials.5c00658<\/a><\/li>\n\n\n\n
  15. Kolte, S.S., Vijayan, V., and Lou, L. Application of Polymer Nanocomposites in the Design of Prosthetic Sockets That Feature Auxetic Meta-Structures. Journal of Applied Polymer Science<\/em>. July 2025 https:\/\/doi.org\/10.1002\/app.57628<\/a><\/li>\n\n\n\n
  16. Zhou, S., Li, P., Yin, S., Lu, Y., Wang, J., Hu, X., Zhang, X., Deng, L., Liu, Y., Luo, X. and Wang, J., Improved adhesion between glass fiber and PAAm\/SA hydrogel via a synergy strategy. Polymer Composites<\/em>. April 2025 https:\/\/doi.org\/10.1002\/pc.29877<\/a><\/li>\n\n\n\n
  17. Shen, H., Guo, W., Wang, J., An, Y. and Lou, L., 2025. Investigating heat generation and transfer in hygroscopic and exothermic textiles by 3D numerical model. International Communications in Heat and Mass Transfer<\/em>, 165<\/em>, p.109053. https:\/\/doi.org\/10.1016\/j.icheatmasstransfer.2025.109053<\/a> <\/li>\n\n\n\n
  18. *Isaac, L., *Charlette, A., *Basik, K., *Conte, M., *Lemmon, S., *Johnson, A., *Davis, W., Vijayan, V., Lou, L.(2025, April). Integrating Biomechanical Mimicry in 3D-Printed Scaffolds for Anterior Cruciate Ligament Reconstruction. Poster presentation at Clemson University 20th Annual Focus on Creative Inquiry Forum, Clemson, SC.<\/li>\n\n\n\n
  19. Agarwal, Arvind, Omar Blandon Cruz, and Lihua Lou. “Devices and methods for nanofiber-based membrane fabrication.” U.S. Patent No. 12,234,575. 25 Feb. 2025. US12234575B1 – Devices and methods for nanofiber-based membrane fabrication – Google Patents<\/a> <\/li>\n\n\n\n
  20. Lou, L., Al-Duhni, G.S.G., Cruz, O.B., Volakis, J.L., Pulugurtha, M. and Agarwal, A., 2025. Iron Oxide Quantum Dots and Graphene Nanoplatelets Integrated in a Dual-Polymer Conductive Fiber for Electromagnetic Interference-Shielding Thin Films. ACS Applied Nano Materials<\/em>. DOI: https:\/\/pubs.acs.org\/doi\/10.1021\/acsanm.4c07086<\/a><\/li>\n\n\n\n
  21. Lou, L., Lopez, K.O., Nair, A.B., Desueza, W. and Agarwal, A.,2024. Micro-Mechanosensory insights from Nature\u2019s Mimosa leaves to shape memory adaptive robotics. Materials & Design<\/em>, p.113567. DOI: https:\/\/doi.org\/10.1016\/j.matdes.2024.113567<\/a><\/li>\n\n\n\n
  22. US20240400767A1, Agarwal, Arvind, Ambreen Nisar, Lihua Lou, and Benjamin Peter Boesl. “HYBRID CARBON NANOFIBERS PRODUCTS AND METHODS OF FABRICATING THE SAME.” U.S. Patent Application 18\/181,338, filed December 5, 2024. <\/li>\n\n\n\n
  23. Ewoldt, J.K., DePalma, S.J., Jewett, M.E., Karakan, M.\u00c7., Lin, Y.M., Mir Hashemian, P., Gao, X., Lou, L., McLellan, M.A., Tabares, J. and Ma, M., 2024. Induced pluripotent stem cell-derived cardiomyocyte in vitro models: benchmarking progress and ongoing challenges. Nature Methods<\/em>, pp.1-17. DOI: https:\/\/doi.org\/10.1038\/s41592-024-02480-7<\/a><\/li>\n\n\n\n
  24. Dong, D., Lou, L., Agarwal, A. and Bhansali, S., 2024, August. Direct Observation of Reversible Surface Potential in Pseudocapacitive Electrochromic Films by Kelvin Probe Force Microscopy. In Electrochemical Society Meeting Abstracts 245<\/em> (No. 51, pp. 2765-2765). The Electrochemical Society, Inc.<\/li>\n\n\n\n
  25. Mirza, A., Hsu, C.P.D., Rodriguez, A., Alvarez, P., Lou, L., Sey, M., Agarwal, A., Ramaswamy, S. and Hutcheson, J., 2024. Computational Model for Early-Stage Aortic Valve Calcification Shows Hemodynamic Biomarkers. Bioengineering<\/em>, 11<\/em>(10), p.955. DOI: https:\/\/doi.org\/10.3390\/bioengineering11100955<\/a><\/li>\n\n\n\n
  26. Somu, D.R., Fuentes, M., Lou, L., Agarwal, A., Porter, M. and Merk, V., 2024. Revealing chemistry-structure-function relationships in shark vertebrae across length scales. Acta Biomaterialia<\/em>. DOI: https:\/\/doi.org\/10.1016\/j.actbio.2024.09.041<\/a><\/li>\n<\/ol>\n\n\n\n

    Year 2024<\/strong><\/p>\n\n\n\n

      \n
    1. Lihua Lou, Rubfiaro, A. S., Deng, V., He, J., Thomas, T., Roy, M., … & Agarwal, A. (2024). Harnessing 3D Printing and Electrospinning for Multiscale Hybrid Patches Mimicking the Native Myocardium. ACS Applied Materials & Interfaces<\/em>. DOI: https:\/\/doi.org\/10.1021\/acsami.4c06505<\/a><\/li>\n\n\n\n
    2. Paul, T., Dolmetsch, T., Lihua Lou, & Agarwal, A. (2024). Frictional resistance and delamination mechanisms in 2D tungsten diselenide revealed by multi-scale scratch and in-situ observations. Nanotechnology<\/em>, 35<\/em>(39), 395703. DOI: https:\/\/doi.org\/10.1088\/1361-6528\/ad5dbe<\/li>\n\n\n\n
    3. Lihua Lou, Dolmetsch, T., Aguiar, B.A., Mohammed, S.M.A.K. and Agarwal, A., 2024. Quantum Dots on a String: In Situ Observation of Branching and Reinforcement Mechanism of Electrospun Fibers. Small<\/em>, p.2311073. DOI: https:\/\/doi.org\/10.1002\/smll.202311073<\/a><\/li>\n\n\n\n
    4. Lihua Lou, Bacca, N., Ma, M.S., Nautiyal, P., Bifano, T.G. and Agarwal, A., 2024. Multiscale mechanics of polydimethylsiloxane: A comparison of meso\u2010and micro\u2010cyclic deformation behavior. Journal of Applied Polymer Science<\/em>, 141<\/em>(25), p.e55546. DOI: https:\/\/doi.org\/10.1002\/app.55546<\/a><\/li>\n\n\n\n
    5. Agarwal, V., Nisar, A., Sukumaran, A.K., Lihua Lou and Mohammed, S.M., 2024. Synergistic Effect of Spark Plasma Sintering Driven Solid-Solution Phases on Scratch Resistance in Two-Dimensional Materials. Lubricants<\/em>, 12<\/em>(2), p.31. DOI: https:\/\/doi.org\/10.3390\/lubricants12020031<\/a><\/li>\n\n\n\n
    6. Rubfiaro, A.S., Prajapati, N.J., Lihua Lou, Ghimire, G., Agarwal, A. and He, J., 2024. Improving the development of human engineered cardiac tissue by gold nanorods embedded extracellular matrix for long-term viability. Nanoscale<\/em>. DOI: https:\/\/doi.org\/10.1039\/D3NR05422E<\/a><\/li>\n\n\n\n
    7. Dong, Dongmei, Lihua Lou, Arvind Agarwal, and Shekhar Bhansali. “Direct Observation of Reversible Surface Potential in Pseudocapacitive Electrochromic Films by Kelvin Probe Force Microscopy.” In 245th ECS Meeting (May 26-30, 2024)<\/em>. ECS, 2024. Link: Direct Observation of Reversible Surface Potential in Pseudocapacitive Electrochromic Films by Kelvin Probe Force Microscopy (confex.com)<\/a><\/li>\n<\/ol>\n\n\n\n

      Year 2023<\/strong><\/p>\n\n\n\n

        \n
      1. Kazue O. L., Dolmetsch, T., Lihua Lou, Thomas, T., Boesl B., and Agarwal, A., 2023. Orientation-Dependent Thermal and Mechanical Properties of 2D Boron Nitride Nanoplatelet Foams via Freeze-Drying. ACS Appl. Nano Mater<\/em>. DOI: https:\/\/doi.org\/10.1021\/acsanm.3c03289<\/a><\/li>\n\n\n\n
      2. Lihua Lou, Rubfiaro, A.S., He, J. and Agarwal, A., 2023. Understanding Spatiotemporal Mechanical Behavior, Viscoelasticity, and Functions of Stem Cell-Derived Cardiomyocytes. Nanoscale<\/em>. DOI: https:\/\/doi.org\/10.1039\/D3NR01553J<\/a><\/li>\n\n\n\n
      3. Lihua Lou, Paolino, L. and Agarwal, A., 2023. Bridging the Gap in Ashby\u2019s Map for Soft Material Properties for Tissue Engineering. ACS Applied Materials & Interfaces<\/em>. DOI: https:\/\/doi.org\/10.1021\/acsami.3c04331<\/a><\/li>\n\n\n\n
      4. Ma, M. S., Subramanian S., Lihua Lou, Arvind A., Christopher S. C., and Thomas G. B. High Throughput Screening System for Engineered Cardiac Tissues. Frontiers in Bioengineering and Biotechnology<\/em> 11: 703. DOI: https:\/\/doi.org\/10.3389\/fbioe.2023.1177688<\/a><\/li>\n\n\n\n
      5. Nisar, A., Lihua Lou, Boesl, B. and Agarwal, A., 2023. Enhanced flexibility and thermal conductivity of HfC decorated carbon nanofiber mats. Carbon<\/em>, 205<\/em>, pp.573-582. DOI: https:\/\/doi.org\/10.1016\/j.carbon.2023.01.055<\/a><\/li>\n\n\n\n
      6. Jiang, P., Lihua Lou and Ramkumar, S., 2023. Comparison of Oil Sorption Capacity of Nonwoven Sorbents. AATCC Journal of Research<\/em>, 10<\/em>(2), pp.101-109. DOI: https:\/\/doi.org\/10.1177\/24723444221132053<\/a><\/li>\n\n\n\n
      7. Sesena-Rubfiaro, A., Prajapati, N.J., Paolino, L., Lihua Lou, Cotayo, D., Pandey, P., Shaver, M., Hutcheson, J.D., Agarwal, A. and He, J., 2023. Membrane Remodeling of Human-Engineered Cardiac Tissue by Chronic Electric Stimulation. ACS Biomaterials Science & Engineering<\/em>, 9<\/em>(3), pp.1644-1655. DOI: https:\/\/doi.org\/10.1021\/acsbiomaterials.2c01370<\/a><\/li>\n\n\n\n
      8. Lihua Lou, Rodrigues de Oliveira, N., Sahani, R., Sukumaran, A.K., John, D. and Agarwal, A., 2023. Localized Nanoindentation Paradigm for Revealing Sutured Tissue Interface Mechanics and Integrity. ACS Applied Bio Materials<\/em>, 6<\/em>(2), pp.908-918. DOI: https:\/\/doi.org\/10.1021\/acsabm.2c01091<\/a><\/li>\n\n\n\n
      9. Li, H., Sundaram, S., Hu, R., Lihua Lou, Sanchez, F., McDonald, W., Agarwal, A., Chen, C.S. and Bifano, T.G., 2023. Dynamic control of contractile force in engineered heart tissue. IEEE Transactions on Biomedical Engineering<\/em>. DOI: https:\/\/doi.org\/10.36227\/techrxiv.15025236.v1<\/a><\/li>\n\n\n\n
      10. Dong, D., Lihua Lou, Lopez, K.O., Agarwal, A. and Bhansali, S. Revealing Nanomechanical Deformation at Interface and Degradation in All-Thin-Film Inorganic Electrochromic Device. Nanoscale <\/em>(2023). DOI: https:\/\/doi.org\/ 10.1109\/TBME.2023.3239594<\/u><\/a><\/li>\n\n\n\n
      11. Yu, W., Lihua Lou, Reynolds, M., Sawhney, P. and Ramkumar, S. Effect of Test Parameters on Sensitivity of Tensile Test Results for Greige Cotton Hydroentangled Nonwoven Fabric. AATCC Journal of Research <\/em>(2023), 10<\/em>(1), pp.10-17. DOI: https:\/\/doi.org\/10.1177\/24723444221132329<\/a><\/li>\n\n\n\n
      12. DeForest, Tinsley Elizabeth, Shekhar Bhansali, Frank K. Urban, Dongmei Dong, Lihua Lou, Arvind Agarwal, Sofia Pinzon et al. “Exploring the Dielectric Properties of Lanthanide Oxide Thin Films.” In 244th ECS Meeting (October 8-12, 2023)<\/em>. ECS, 2023. (Published Conference Paper) Link: 244th ECS Meeting (October 8-12, 2023) (confex.com)<\/a><\/li>\n<\/ol>\n\n\n\n

        Before 2023<\/strong><\/p>\n\n\n\n

          \n
        1. Lihua Lou, Paul, T., Aguiar, B.A., Dolmetsch, T., Zhang, C. and Agarwal, A. “Direct Observation of Adhesion and Mechanical Behavior of a Single Poly (lactic-co-glycolic acid)(PLGA) Fiber Using an In Situ Technique for Tissue Engineering.” ACS Applied Materials & Interfaces<\/em> (2022). DOI: https:\/\/doi.org\/10.1021\/acsami.2c09665<\/a><\/li>\n\n\n\n
        2. Lin, Y. M., Lia P., Lihua Lou, Ariadna H., Erika P., Arvind A., and Sharan R. “Directional Dependence on Concomitant Pressure and Volume Increases During Left Ventricular Filling.” Journal of Biomechanics<\/em> (2022): 111129. DOI: https:\/\/doi.org\/10.1016\/j.jbiomech.2022.111129<\/a><\/li>\n\n\n\n
        3. Lihua Lou, Kazue O. L., Pranjal N., Arvind A. “Integrated Perspective of Scaffold Designing and Multiscale Mechanics in Cardiac Bioengineering.” Advanced NanoBiomed Research <\/em>(2021). DOI: https:\/\/doi.org\/10.1002\/anbr.202100075<\/a><\/li>\n\n\n\n
        4. Lihua Lou<\/a>, Rubfiaro, A. S., He, J., Agarwal, A., Effect of Electrical Stimulation on Spontaneously Beating Dynamics of Cardiac Tissues: An Analysis Using Digital Image Correlation. Advanced Material Technology <\/em>2021, 2100669. DOI: 10.1002\/admt.202100669<\/li>\n\n\n\n
        5. Odia O., Lihua Lou (co-1st<\/sup> author), Smith E., Seshadri R. Nanofibrous substrate for tissue engineering applications. AATCC Journal of Research<\/em>, 2021. DOI: https:\/\/doi.org\/10.14504\/ajr.8.6.2<\/a><\/li>\n\n\n\n
        6. Lihua Lou, Yu, W., Kendall, R. J., Smith, E., & Ramkumar, S. S. (2020). Tensile testing and fracture mechanism analysis of polyvinyl alcohol nanofibrous webs. Journal of Applied Polymer Science<\/em>, 49213. DOI: 10.1002\/app.49213<\/li>\n\n\n\n
        7. Lihua Lou, Odia O., and Seshadri S. R. “Functional Nanofibers and Their Applications.” Industrial & Engineering Chemistry Research<\/em> (2020). DOI: https:\/\/doi.org\/10.1021\/acs.iecr.9b07066<\/a><\/li>\n\n\n\n
        8. Lihua Lou, Ronald J. K., and Seshadri R. “Comparison of Hydrophilic PVA\/TiO2 and Hydrophobic PVDF\/TiO2 Microfiber Webs on the Dye Pollutant Photo-catalyzation.” Journal of Environmental Chemical Engineering<\/em> (2020): 103914. https:\/\/doi.org\/10.1016\/j.jece.2020.103914<\/a><\/li>\n\n\n\n
        9. Chai, G.H., Amr H., Tuo M., Lihua Lou, Jonathan M., Russell S., Lei Z., Bruce K. R., Qi (Tony) Z., P. Worth L., Michael H., Qingguo X. “Dry powder aerosol containing muco-inert particles for excipient enhanced growth pulmonary drug delivery.” Nanomedicine: Nanotechnology, Biology and Medicine<\/em> (2020): 102262. https:\/\/doi.org\/10.1016\/j.nano.2020.102262<\/a><\/li>\n\n\n\n
        10. Lihua Lou, Seenivasan S., Ramkumar S., Ernest S., Ronald J. K. Functional PVA\/VB2\/TiO2 Nanofiber Webs for Controlled Drug Delivery[J]. ACS Applied Bio Materials<\/em>, 2019. DOI: https:\/\/doi.org\/10.1021\/acsabm.9b00726<\/a><\/li>\n\n\n\n
        11. Lihua Lou, Ronald J. K., Ernest S., Ramkumar S*. Functional PVDF\/rGO\/TiO2 nanofiber webs for waste oil\/water treatment[J]. Polymer<\/em>, 2019: 122028. DOI: https:\/\/doi.org\/10.1016\/j.polymer.2019.122028<\/a><\/li>\n\n\n\n
        12. Lihua Lou, Wang J, Yong-Joon L, Ramkumar S*. Visible Light Photocatalytic Functional TiO2\/PVDF Nanofibers for Dye Pollutant Degradation[J]. Particle & Particle Systems Characterization<\/em>, 36, 1900091, 2019. [Cover image] DOI: https:\/\/doi.org\/10.1002\/ppsc.201970025<\/a><\/li>\n\n\n\n
        13. Wang J, Lihua Lou, Qiu J*. Super\u2010tough hydrogels using ionically crosslinked networks[J]. Journal of Applied Polymer Science<\/em>, 136, 48182, 2019. DOI: https:\/\/doi.org\/10.1002\/app.48182<\/a><\/li>\n\n\n\n
        14. Lihua Lou, Wang J, Ramkumar S*. Optimization of testing parameters for tensile property evaluation of poly (vinyl alcohol) nanofibers webs[J]. Journal of Applied Polymer Science<\/em>, 136, 47159, 2019. DOI: https:\/\/doi.org\/10.1002\/app.47159<\/a><\/li>\n\n\n\n
        15. Lou L, Yu W, Ramkumar S. Editor: Roshan Paul. Wearable and Smart Responsive Textiles. in High Performance Technical Textiles. Wiley, Chennai, India, 2019: 439-473. DOI: https:\/\/doi.org\/10.1002\/ppsc.201970025<\/a><\/li>\n\n\n\n
        16. Lihua Lou, Qin X H*, Zhang H. Preparation and study of low-resistance polyacrylonitrile nano membranes for gas filtration[J]. Textile Research Journal<\/em>, 87, 208-215, 2017. DOI: https:\/\/doi.org\/10.1177\/0040517515627171<\/a><\/li>\n<\/ol>\n\n\n\n

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