Cell Culture and Fermentation
Optimization Lab
Recent Alumni


Swadeel Gaad

Swadeel Gaad

I was born in Goa, India. I moved to Clemson to pursue my Master’s Degree in Electrical Engineering with Intelligent systems as my focus area. I have developed algorithms and tools for underwater image processing towards the completion of my bachelor’s degree in Electronics and Telecommunication at Goa College of Engineering. I have worked with robotics and Internet of things in my undergrad. I helped in developing “Bolt” which is an internet of things platform that helps you to control any household devices with your cell-phone or laptop over the internet. Currently I am working in collaboration with the Bioengineering department under Dr. Sarah Harcum and Electrical and Computer Engineering department under Dr. Richard Groff to develop adaptive control system for fast and stable growth for recombinant CHO cells.



Timothy Lindquist


Timothy Lindquist

I was born in Morristown, NJ, and graduated from Clemson University with a BS in Bioengineering in May of 2018. After taking Dr. Harcum’s Biopharmacuetical Engineering course, I was interested to learn more about the upstream processes for the development of biologics, and began conducting undergraduate research in her lab. In the summer of 2018, I had an internship at Pfizer, where I worked in an analytical research and development oncology group optimizing reduction kinetics for antibody drug conjugates. For my MS project, I will be working with CHO cell process development. In my free time, I enjoy fishing, playing the drums/ piano, and attending Clemson football games.



Shahin Lashkari

Shahin Lashkari

I got my bachelor’s from Amirkabir University of Technology and my master’s from Sharif University of Technology both in mechanical engineering. Then I came to Clemson University to continue my studies. While studying at Clemson University, I became fascinated with interdisciplinary fields of research such as applying control concepts in bioengineering. I joined the team of graduate students supervised by Dr. Harcum and Dr. Groff from bioengineering and electrical engineering departments. My research is designing a controller which can set the appropriate feed rate based on the metabolic state of E. coli bacteria. By designing a robust metabolic state detector which can detect whether the cells are in oxidative or overflow state, the controller can increase or decrease the feed rate based on the response of the cells. The controller maintains the cells close to the boundary of oxidative and overflow (BOOM) states, which assures the efficient growth for the cells before and after the induction.




Daniel Infante

I was born in Bogota, Colombia, and lived there until I was seven years old. I then moved to the United States and lived in Baltimore, MD, for a couple months before settling in Atlanta, GA, where I grew up. I received my BS in Bioengineering with a biomaterials concentration from Clemson University in May 2017. My undergraduate research involved investigating the structural degradation and calcification of bioprosthetic heart valves. For my MS project, I will be working with E. Coli and how a particular strain responds to different feeding methods.

Undergraduate and Graduate Student Alumni Group Photos



Left to right: Mary Alice Salazar, Kristen Publicover, Mary Caldwell, Kyle Bennett, Sarah Harcum, Lauren Staples, Robin Winchester, Lauren Bruneau



Left to right: Brad Harris, Shamik Sharma, Peifeng Chen, Kevin Clark, Fu'ad Haddadin


Left to right: Antonia Perez, Kristen Publicover Miller, Lauren Staples, Mary Alice Salazar
 
Graduate Student Alumni Information
Name and Degree Thesis Title Current Position
Yogender K. Gowthan,
Ph.D Bioengineering, May 2016
Master's, Bioengineering Dec. 2014
Understanding the transcriptional landscape of Chinese hamster ovary (CHO) cells using next-generation sequencing technology, RNA-seq, under industrially relevant conditions KBI Biopharma
Arthur Nathan Brodsky,
Ph.D Bioengineering, August 2015
Master's Bioengineering, May 2013
Investigations into the Dynamics of Mammalian Cell Growth: Using in vitro Insights to Help Improve Therapies Cancer Research Institute
Eric R. Bandstra
(co-advised with Ted Bateman as primary),
Ph.D Bioengineering, May 2008
The spaceflight environment and the skeletal system Naval Medical Research Unit (NAMRU)
Shamik S. Sharma,
Ph.D Chemical Engineering, Aug. 2005
Recombinant Protein Production from E. coli Fermentations: Use of Intein Fusion Proteins and Reduced Genome E. coli Strains Pfizer
Peifeng Chen,
Ph.D Chemical Engineering, May 2005
Ammonium Toxicity and Amino Acid Protection in Chinese Hamster Ovary Cells National Institutes of Health
Fu’ad Haddadin,
Ph.D Chemical Engineering, May 2004
Genetic response recombinant Escherichia coli during protein overexpression CSL Behring
Kevin J.-R. Clark,
Ph.D. Chemical Engineering, May 2004
A study of production and product quality related issues of recombinant proteins Janssen
Even Skjervold,
Master's Bioengineering, Dec. 2014
Non-Thesis YeastSouth
Faraz Baig,
Master's Bioengineering, May 2013
Dynamic transcriptional response of Escherichia coli to inclusion body formation Baxter
Kristen Publicover Miller
(co-advised with Michael Hensen),
Master's Microbiology, Dec. 2010
Biofuel ethanol production by Saccharomyces bayanus, the champagne yeast Clemson University
Mary Alice Salazar,
Master's Analytical Chemistry, May 2010
Comparison of RNA Quality From Stressed And Unstressed Recombinant Escherichia coli University of Texas
Dzung Bui,
Master's Chemical Engineering, May 2003
Economic Feasibility of an Intein-Based Chromatography Separation Method for Tissue Plasminogen Activator City of Las Cruces
Gary Jordan,
Master's Chemical Engineering, May 2000
Characterization of Proteases induced in an Industrial Recombinant Protein Fermentation
Adriana L. Batista Marulunda,
Master's Chemical Engineering, May 1998
Removal of metal ions from acid mine drainage by immobilized algal biomass El Paso Water
Michelle H. Barragan Alba,
Master's Chemical Engineering, Aug. 1997
The feasibility of using Cyanadium caldarium to bioremediate copper from acid mine drainage Jacobs Technology
Seong Doo Yoo,
Master's Chemical Engineering, May 1997
Temperature Effects on the Degradation of Waste Sugar Beet Pulp by Xanthomonas campestris
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