Laboratory of Orthopaedic Tissue Regeneration and Orthobiologics


Welcome to the Laboratory of Orthopaedic Tissue Regeneration and Orthobiologics
(OrthO-X Lab)!


Our lab focuses on the development of regenerative medicine technologies used to restore the anatomy and physiology of damaged or diseased musculoskeletal tissues (including intervertebral discs, articular cartilage and tendons). Our general approach involves engineering biomaterials which mimic the native tissue micro-architecture and serve as support structures for various cell sources including primary cells derived from orthopaedic tissues as well as different populations of stem cells. We are currently undertaking multiple projects which span the research and development continuum including projects which are short-term and may be directly translatable into a clinical application to those which are considered basic science or experimental (geared towards understanding orthopaedic disease processes or regenerating tissues from the ground up).

The lab was founded in August 2013 by Jeremy Mercuri, PhD and is composed of both graduate and undergraduate students who work diligently together to lead projects and maintain collaborations with clinicians and medical device industry representatives.

We want to thank you for visiting our website and for your continued interest in our research group. Please feel free to leave us a message if you have any further questions or would like to get in contact with us directly. You can also follow us on our twitter page @MercuriLab.

1. Congratulations Josh Walters for earning his PhD!!      2. Congratulations Vishal Thomas for winning the 3 minute thesis competition.       3. Congratulations Karenna Smith for winning 1st place in the Undergraduate student poster competition at the 2019 ASGSR conference.      4. Ortho-X lab was awarded a technology maturation grant for its osteochondral implant.      5. Congratulations Karenna Smith and Mario Krussig for earning your undergraduate degree.      6.Congratulations Dr. Mercuri for being named the John Witherspoon Gilpin, MD ’82 Endowed Associate Professor of Bioengineering.