NANOBIOTECHNOLOGY LAB

RNAi - DRUG DELIVERY - BIOMATERIALS - NANOTECHNOLOGY

BIOE 4480 - Tissue Engineering

 

3 Credits (2 Contact Hours)

Explores the application of engineering principles toward the development of biologically based substitutes that restore, maintain, or improve tissue function. Topics include biodegradable scaffolds, wound healing and tissue repair, cell-matrix interactions, immunology and biocompatibility, stem cells. Preq: BIOE 3020 and BIOL 3150. Preq or concurrent enrollment: BIOL 4610. Coreq: BIOE 4481.

 

BIOE 4481 - Tissue Engineering Laboratory

 

0 Credits (3 Contact Hours)

Non-credit laboratory to accompany BIOE 4480. Coreq: BIOE 4480.

 

 

BIOE 4420/6420 - Biomedical Applications of Gene Regulation and Editing

 

3 Credits

The course begins with an overview of the basis of genes, the process of how the genetic code gives rise to proteins and is regulated in eukaryotic cells, and genetic mutations. Later we will cover delivery methods and cutting-edge molecular tools for altering protein expression, manipulating the genome, design, analysis and their application. We will explore applications of gene editing from the literature for making model organisms and gene therapy for inherited and acquired diseases. The course will conclude with ethical and biosafety considerations of gene editing. Preq: BCHEM 3050

 

 

BIOE 4510 (001) - Creative Inquiry - "Image-Guided Drug Delivery to the Brain"

 

Variable credits

Students will work together to develop nanoparticle systems capable of delivering FDA approved contrast agents directly to the site of interest in the brain, with the goal of limiting toxicity associated with whole body exposure and off-targeting. Due to their small size, nanoparticles have the ability to load a high concentration of drug while simultaneously being targeted to specific areas of the brain, which would provide a dramatic improvement to current CT capabilities.

 

 

BIOE 4510 (004) - Creative Inquiry - "Diversity Outreach in Bioengineering"

 

Variable credits

This CI will function as a diverse cohort of students seeking to enroll in Bioengineering. Students will be immersed in various hands-on applied bioengineering projects to give them exposure to bioelectrical and biomaterials engineering. Throughout the semester, students will work in teams to design various types of bionic arms, synthesize biomaterials, and learn essential concepts in tissue engineering. We will also facilitate connections between freshmen with upperclassmen and grad students in bioengineering as they work together on a multidisciplinary engineering project.

 

 

 

ANGELA ALEXANDER-BRYANT

Assistant Professor

 

Director of Diversity and Inclusion

 

Department of Bioengineering

Clemson University

 

Office: 501-3 Rhodes Research Center

Clemson University

Clemson, SC 29634

 

Email: AngelaA@clemson.edu

Phone: 864-656-5232