Welcome to the Systems Mechanobiology Lab!
Our lab focuses on matrix systems mechanobiology, and two primary questions:
1. How do mechanical and biochemical signals regulate cell and tissue behaviors related to extracellular matrix remodeling?
2. How can we predict and control this complex regulatory system to diagnose, treat, and prevent fibrotic diseases?
To answer these questions, we are developing computational systems models alongside high-throughput in vitro tissue culture platforms in order to engineer novel technologies for controlling fibrotic remodeling related to heart failure, wound healing, and other disease conditions.