One of the major goals of the SC TRIMH Center is to improve the capacity and capabilities of the infrastructure and resources available to investigators to perform cutting-edge musculoskeletal health research, and medical research in general, at Clemson and across the state and southeast.
The SC TRIMH Research Cores were developed by leveraging Clemson’s existing strengths in biophysics/computational modeling, advanced additive/subtractive manufacturing and systems analysis and assessment, and preclinical modeling and functional assessment, into three comprehensive Research Cores. The Multiscale Computational Modeling goals and services are described below.
Hai Yao, DirectorAdam Hoover, Co-Director
Objective: Support to build patient-specific and precision-care musculoskeletal systems through multiscale modeling at molecular, cellular, tissue, and body levels.
Go-to Place for Multiscale and Multi-discipline computational modeling
Services:
High-performance graphic workstations for imaging-based model creation (pre-processing) and simulation results visualization (post-processing).
High-performance computing workstations for computational model solver optimization.
Commercial software licenses and modeling software capacities through open-source codes like FEBio (finite element analysis), OpenSim (multibody dynamics), and 3D slicer (imaging processing).
Full access to high-performance computing and data visualization capacities at Clemson through Clemson Cyberinfrastructure Technology Integration (CITI) Group within Clemson.
Support team to provide general and project-specific assistances in multiscale computational – molecular, cellular, tissue-level modeling.
Capacities on pre and post-processing in computational modeling.
COMSOL, ABQUS, ANSYS, FLUENT, etc., + multibody human dynamics modeling using AnyBody and OpenSim, probabilistic modeling using Molecular Dynamics codes, and image-based patient-specific modeling using Amira, Mimics, and Simpleware.
AI/ML based modeling.
Resource Mentors: Feng Ding - Resource Mentor - molecular dynamics modeling Jill Gemmill - Resource Mentor - all matters concerning Palmetto Cluster related software and training issues Hudson Smith - Resource Mentor - AI/ML application and mentoring Yongren Wu - Resource Mentor - patient-specific multiscale biomechanical modeling of musculoskeletal systems
