THE COTTLE GROUP
Principal Investigator: Dr. Renee Cottle
RESEARCH
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Renee Cottle, Ph.D.
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Cas9 Immunogenicity in Liver Gene Therapy
Cell-Based Therapy for Familial Hypercholesterolemia
Cryopreservation of Gene-Edited Primary Hepatocytes
Electroporation-Based Cell Therapy for Pediatric Patients
Lipid Nanoparticle-Mediated Gene Editing Therapy
NGS Analysis of Genomic Stability
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RESEARCH
Cas9 Immunogenicity and Its Impact on Liver-Directed Gene Therapy for Inherited Metabolic Liver Diseases
Electroporation-Mediated Multiplex Gene Editing and Selection: Disease-Tailored Gene Therapy for Familial Hypercholesterolemia
Electroporation-Mediated Cryopreservation of Gene-Edited Primary Hepatocytes for Treating Inherited Metabolic Liver Diseases
Neonatal Hepatocytes Tolerate Electroporation-Mediated Gene Editing and Engraft in the Liver
Lipid Nanoparticle-Mediated Delivery of CRISPR-Cas9 to Primary Hepatocytes for the Treatment of Hereditary Tyrosinemia Type I
Analysis of Genomic Stability Following Multiplex Gene Editing Using Next-Generation Sequencing Tools
